Since the discovery of A2 β-casein by New Zealand pediatricians in 1993, scientists' research on A2 protein has never stopped. Further research has further confirmed the benefits of A2 protein; the expansion of the research scope has made more benefits of A2 protein. Discovered and increased consumer awareness of dairy products containing A2 β-casein.
Research scope further expands, A2 protein may benefit children's cognitive performance
Research on A2 protein for children has been closely followed by scientists in recent years, and progress has been made again a few days ago.
Recently, the impact of ordinary milk and milk containing only A2 β-casein on the digestion of Chinese children: a randomized study published by the authoritative Chinese and Australian experts in the journal "Pediatric Gastroenterology and Nutrition" (Journal of Pediatric Gastroenterology and Nutrition, "JPGN") is published independently. The study found that milk containing only A2 β-casein (hereinafter referred to as “A2 protein milk”) can alleviate gastrointestinal symptoms caused by milk intolerance in Chinese preschool children and can improve their cognitive performance accordingly. The study initially explored the potential benefits of A2 protein in children's cognitive performance, and also extended the study of A2 protein to new areas.
JPGN was founded and published in 1982. It is an authoritative academic journal focusing on pediatric gastroenterology, hepatology and nutrition. It is also considered one of the top journals in the field of pediatrics. It is also the official academic journal of the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), and the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN).
This multicenter, double-blind, randomized, controlled, parallel, crossover study showed that in preschool children who reported mild to moderate discomfort after milk intake, switching to A2 protein milk significantly reduced gastrointestinal Tract symptom score and improved gastrointestinal symptoms. At the same time, the study also compared the cognitive behavior changes of the preschool children based on the Fine Cognitive Impairment Test (SCIT), and the results showed that their cognitive performance improved accordingly.
Professor Stephen Robinson, Director, Department of Psychology, RMIT University, and Director, Australian Brain Foundation
SCIT is a test method for children's cognitive performance generally recognized by the international academic community. As the academic authority in this field, Professor Stephen Robinson, the director of the Department of Psychology at RMIT University and the director of the Australian Brain Foundation, although he was not involved in this research, he paid close attention to this research and published an independent opinion: the method used in this research was It is widely used in clinical research and meets international standards. Its technical term is double-blind, cross-research. At the same time, he pointed out that the detailed cognitive impairment test (SCIT) in the study mainly looked at two parameters, response speed and number of errors. What is worth noting in this experiment is the number of mistakes made by the subjects. Those who consumed A2 protein milk performed better. From a statistical perspective, the difference between the two groups is significant.
In recent years, scientists have confirmed through a large number of studies that there is a bidirectional effect between the central nervous system and the gastrointestinal system. The close relationship between the gastrointestinal tract and the brain enables the gastrointestinal tract to exert a two-way influence on the brain through the "brain-gut axis" during the process of digesting and absorbing food. The digestive system and brain of infants and children are in the developmental stage and are more immature and sensitive than adults. As for milk, a food that plays an important role in their dietary structure, the effects on their digestive system and brain may be More significant.
Professor Felice Jacka, director of the Centre for Food and Emotions at Deakin University in Australia and founder and chairman of the International Nutritional Psychology Association, said: "We already know the importance of 'what to eat' for our health. But in the past decade, we have gone further Recognizing what to eat is also important to our cognition and brain health, including the learning and memory capabilities associated with this study. "
Professor Bob Elliott, Retired Emeritus Professor of Pediatrics, University of Auckland
"Recent clinical trials in Chinese adults and children have brought a new milestone in human A2 protein research," said Professor Bob Elliott, a retired emeritus professor of pediatrics at the University of Auckland. "Research conducted in Chinese adults and children shows that Subjects who ingested A2 protein milk performed better in the digestive tract, inflammation, immune response and brain function. Past research was more based on epidemiological categories, but I think these recent studies have allowed A2 protein milk to enter more The broad field of research plays a decisive role. "
Professor Dennis Savaiano, of the Department of Nutritional Science, Purdue University, Indiana, USA, who has a high degree of authority in this academic field, commented: "This research method is well-designed-double-blind, random, and crossover. It is the gold standard for scientific design." "Evidence for children with fewer intolerance symptoms after ingesting A2 protein milk is clear. The results of this study are not only consistent with previous studies in adults, but also in current adult clinical trials in the United States. Together. "
Professor Dennis Savaiano, Department of Nutritional Science, Purdue University, Indiana, USA
Professor Dennis Savaiano said: "The evidence related to cognitive function in this study is very intriguing and worthy of further research to find the specific components related to cognitive performance in A2 protein milk, the adaptability to different milk types, and the different Age, relevance in different populations, and contexts. "
The research on the relationship between milk protein and children's cognitive performance may trigger a deeper exploration in the academic world and open up a new academic research direction.
In recent years, heavy research has been frequent, and more potential benefits of A2 protein have been discovered
With the development of scientific research on A2 protein, many international and domestic research results have been published. So far, more than 140 research papers have been published, and the research scope has also covered more fields. In recent years, scientists have frequently published heavy research results, constantly refreshing people's understanding of A2 protein.
In 2016, the New Zealand government contributed $ 1.25 million to support a study on the effects of A2 protein milk on the digestive system. Preliminary findings suggest that some individuals who describe themselves as lactose intolerant may experience gastrointestinal discomfort after ingesting milk that may be related to A1 β-casein in milk.
Chinese scholars' research on Chinese people is also developing. Also in 2016, Professor Sun Jianqin, the director of the Department of Nutrition, East China Hospital Affiliated to Fudan University, conducted the first study on gastrointestinal discomfort in Chinese people after drinking milk in Shanghai. The following year, the Journal of Nutrition published another research result led by Professor Yang Yuexin, the chairman of the Chinese Nutrition Society, with the participation of many well-known experts in the field of nutrition. The clinical trial covered three places in Beijing, Shanghai, and Guangzhou, and was attended by 600 Chinese Han adults. It was also conducted in a double-blind, randomized, cross-over, and peer-review manner. Studies have found that milk containing only A2 β-casein can reduce or reduce the symptoms of acute gastrointestinal discomfort caused by milk intake in some people.
Professor Felice Jacka, Director, Centre for Food and Emotions, Deakin University, Australia, and Founder and Chairman of the International Nutritional Psychology Association
Professor Felice Jacka of Deakin University talked about the research progress of A2 protein: "Diet and nutrition play a very important role in our physical, mental and brain health. Dairy products are an important food for all of us. More and more Evidence shows that dairy products containing only A2 protein are indeed different. We are also very interested in this research topic. In fact, we are conducting a randomized study on Australian women to test milk pairs containing different protein types The effects of women's cognitive, brain, and gut health. "
A2 protein allows more and more people to benefit from milk
With the deepening of basic research, the international academic community has gradually reached a consensus on the benefits of A2 β-casein. It is believed that in future research by scientists, A2 protein will bring more health benefits to humans.